![NewEast/Ras蛋白[10110][100µg]/10110](https://www.ebiomall.cn/images/neweastbio/10110.jpg)
NewEast/Ras蛋白[10110][100µg]/10110
商品编号：
10110
市场价：
¥4780.00
美元价：
2868.00
产品分类：
蛋白纯化试剂盒
公司分类：
Protein_purification_kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Catalog Number: 10110 |
| Product Name: Ras Protein |
| Synonyms: GTPase Ras |
| Source: Human, recombinant full length, His6-tag |
| Expression Host: E. coli |
| Molecular Weight: 21 kDa |
| Purity: >95% by SDS-PAGE |
| Introduction: Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). |
| Amino Acid Sequence (1-189) |
| MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAM RDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLA RSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS |
| Properties |
| Physical Appearance (form): Dissolved in 20mM Tris-HCl, pH8.0, 150mM NaCl. |
| Physical Appearance (form): White or clear |
| Concentration: 1 mg/mL |
| Storage: -80°C |
| Preparation Instructions: Centrifuge the vial before open the cap and reconstitute in water. Adding of 10 mM β-mercaptoethanol or 1 mM DTT into the solution to protect the protein is recommended and using of non-ionic detergents such as n-Dodecyl β-D-maltoside (DoDM) or polyethylene detergents (e.g. C12E10) also help to stabilize the protein. Avoid repeated freezing and thawing after reconstitution. The purity of His-tagged Ras was determined by SDS- PAGE and Coomassie Brilliant Blue Staining. |
 |
| References: 1. Chen, H.-J. et al., Neuron 20: 895-904, 1998. 2. Hamdan, F. F. et al., New Eng. J. Med. 360: 599-605, 2009. 3. Oh, J. S. et al., Neuron 33: 151 only, 2002. 4. Rumbaugh, G. et al., Proc. Nat. Acad. Sci. 103: 4344-4351, 2006. 5. Tomoda, T. et al., Genes Dev. 18: 541-558, 2004. |
Datasheet:  |
| Publications: |
| 1. DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model Gene Therapy 21, 888-896 (October 2014) |
品牌介绍
美国NewEastBio专注于生命科学和生物技术领域，主要产品有抗体、小分子、ELISA试剂盒、蛋白等，与世界著名高校和研究所、世界大制药公司、生物科技公司和医院等客户建立了长期稳定的合作关系，产品销往全球。 美国NewEastBio，负责美国品牌NewEastBio（www.neweastbio.com）产品在中国市场的推广、销售及售后服务。致力于为客户提供一系列高质量和有绝对价格竞争力的美国NewEastBio原装进口产品。并提供专业的技术服务：抗体定制，动物实验等
品牌分类
10μg纯化g蛋白
1x96井生物标志物
100微升单克隆抗体
100ul纯化G蛋白
突变癌基因100微升抗体
96井营地和cGMP环境影响评价工具包
30微升活性单克隆抗体
100微升生物标志物
30微升生物标志物
联络我们
服务热线：4000-520-616
（限工作日9:00-18:00）
QQ ：1570468124
手机：18915418616
